Figure 2.

αPS3 Integrin is required for lumen formation. The lumen of the Drosophila heart is developed in stage 17 wildtype embryos (arrow), between contralaterally apposed cardioblasts (c). No lumen develops between cardioblasts in scb2 mutant embryos (B), however, there is partial restoration of the lumen (arrow, C) in scb2 mutant embryos expressing an αPS3 transgene (scb2/scb2; dMEF-GAL4/UAS-αPS3). Sections were sampled between abdominal segments 6-8. Ectodermal cells (e) and amnioserosa cells (asterisk) are identified; calibration: 5 microns

Vanderploeg et al. BMC Developmental Biology 2012 12:8   doi:10.1186/1471-213X-12-8
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