Additional file 4 Figure S4.
Expression pattern of the Notch signaling targets Cut and Hnt. (A) Schematic representation of Notch signaling activity. Until stage 5, Delta (Dl) is not expressed by the germline, Notch is not activated in FCs, and Cut is expressed whereas Hnt is absent. By stage 6, Dl is expressed by the germline and activates Notch in FCs, Cut is downregulated, and Hnt is expressed (B) Expression of Cut starting in the germarium and continuing until stage 6. (C) Expression of Hnt is absent in early stages but expression is activated by stage 6. (D) Eggs lacking ATG1 function in both GCs and FCs (marked by the lack of GFP) show normal activation of the Notch pathway with Cut expression levels comparable to WT eggs. Anterior is to the left, posterior to the right. Scale bar: 50 μm (B-C), 20 μm (D). Genotypes: B, C: y w. D: hs flp/+; ATG1∆ 3DFRT80B/FRT80B-UbiGFP.
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Barth et al. BMC Developmental Biology 2012 12:35 doi:10.1186/1471-213X-12-35