Table 2

Comparison of zfDsc exon sizes with three human desmocollin genes

Exon

hDsc1

hDsc2

hDsc3

zfDsc

Protein domain


1

Non-coding

+63

+69

+69

Non-coding

+42

S


2

85

85

85

91

P


3

203

203

203

191

EC1


4

120

120

120

114


5

156

156

156

156

EC2


6

145

145

145

142


7

167

167

167

155

EC3


8

135

135

135

135


9

186

186

186

186

EC4


10

260

257

257

248


11

143

143

143

143

EA


12

213

225

225

222


13

240

237

225

237

TM


14

122

125

122

116

CYT


15

249

258

258

285


16

46

46

43

Non-coding

+213

Alternative splicing


17

Non-coding

+195

195

195

Non-coding

+213

TD


The numbers in bold italics indicate exons having identical sizes. The right hand column shows the approximate corresponding protein domains. S = signal, P = precursor, EC = extracellular, EA = extracellular anchor, TM = transmembrane, CYT = cytoplasmic, TD = terminal domain of human "b" form.

Goonesinghe et al. BMC Developmental Biology 2012 12:1   doi:10.1186/1471-213X-12-1

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