Additional file 8.

Phylogenetic tree showing clustering of all complete sequenced HH proteins (Indian (IHH), Sonic (SHH), desert (DHH), Echidna (EHH), TwiggyWinkle (TWHH)). EHH and TWHH each contain only 1 member, and have both been shown to cluster within IHH and SHH groups respectively. The fish DHH orthologues (FHH) form a separate cluster from the mammalian DHH genes. EHH, TWHH and reported fish DHH orthologues (FHH) are highlighted in red. Node labels are in the format: PROTEIN_Genus_species.

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O'Hara et al. BMC Developmental Biology 2011 11:72   doi:10.1186/1471-213X-11-72