Protein expression in adult human liver/the "remodeled bile duct" stage. (A) The graphical interpretation illustrates that the bile ducts has fully remodeled into the portal mesenchyma, whereas the ductal plate has disappeared. CK7 (B) was now fully expressed by bile duct cells, along with CK19 (C), EpCAM (D), SOX9 (F) and AQP1 (I), whereas the hepatocytes exclusively stained for HepPar1 (E). (G) Laminin was particularly deposited around portal vascular structures, but absent from the sinusoids. (H) Nestin expression could only be found in a few portal vessels (h, arrow). Upper case letters x10, lower case letters x63. Scale bar: 100 μm (for all photos marked with upper cases).
Vestentoft et al. BMC Developmental Biology 2011 11:56 doi:10.1186/1471-213X-11-56