Table 2

Notch112f/tm1Con pups may survive to birth

Stage

12f/12f × +/tm1Con

12f/12f × +/lbd


Litters

Pups

+/12f

12f/tm1Con

Litters

Pups

+/12f

12f/lbd



E9.5

3

23

11

12

5

38

18

20

E10.5

3

23

13

10

8

70

37

33

E11.5

4

24

16

8

7

48

28

20

E12.5

5

25

21

4

8

33

28

5

E13.5

5

27

21

6

5

23

23

0

E15.5

3

13

9

4

-

-

-

-

E17.5

5

19

17

2

-

-

-

-

P1

6

25

23

2

-

-

-

-

Wean

13

50

50

0

8

30

30

0


Embryos (E9.5 -- E17.5), post-natal pups (P1) and mice after weaning were genotyped from crosses of Notch112f/12f female × Notch1+/tm1Con male or crosses of Notch112f/12f female × Notch1+/lbd male. The data from Notch1+/12f × Notch112f/lbd crosses were previously published [12] but are included for ease of comparison.

Ge and Stanley BMC Developmental Biology 2010 10:36   doi:10.1186/1471-213X-10-36

Open Data