Additional file 2.

Sel1l-deficient pancreatic epithelium exhibits impaired growth, branching morphology and differentiation ex vivo. The dorsal pancreatic bud of wild-type (+/+) and Sel1l^βgeo/βgeo (-/-) embryos were isolated at E11.5 and cultured as described in Materials and Methods. Cultured pancreatic explants were immunostained with the indicated antibodies. Sel1l-deficient pancreatic epithelium grows poorly and displays impaired branching morphology (B and D), as compared to wild-type control explants (A and C). Scale bar: 100 μm.

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Li et al. BMC Developmental Biology 2010 10:19   doi:10.1186/1471-213X-10-19