Neural precursor cells prematurely exit the cell cycle and develop as neurons in dlAdx2 mutant embryos. Labeling to detect proliferative cells by BrdU incorporation (brown) and post-mitotic neurons by huC expression (blue) on transverse sections through trunk neural tube. Both proliferative cells and post-mitotic neurons are evident in a wild-type embryo (A) whereas a mutant embryo had many more neurons and fewer proliferative cells (B). Scale bar, 10 μm.
Appel et al. BMC Developmental Biology 2001 1:13 doi:10.1186/1471-213X-1-13