Notch signaling is disrupted in dlA dx2 mutant embryos. Dorsal views, anterior to left, of neural plate stage embryos probed for expression of ngn1. (A) Wild-type embryo showing three longitudinal domains of ngn1 expression. (B) dlAdx2 mutant embryo showing uniformly high level expression of ngn1 in each longitudinal domain. This mutant embryo was slightly older than the wild-type; consequently, the lateral longitudinal ngn1 domains are closer to the embryonic midline. Scale bar, 50 μm.
Appel et al. BMC Developmental Biology 2001 1:13 doi:10.1186/1471-213X-1-13