Additional file 7.

Arp2/3 localises to dynamic and static filopodia. A) Arp2/3 complex containing filopodium from a cell that is actively protruding. A patch of Arp2/3 complex appears in a filopodium before being overtaken by the extending lamellipodium. Images are taken from timelapse movie frames captured every 10 seconds. Scale bar 5 μm. B) Arp2/3 complex containing filopodium from a cell that is not actively protruding. The Arp2/3 complex in this situation is much less dynamic than that seen in additional file 7. This suggests a correlation between the protrusive activity at the site of an Arp2/3 complex containing filopodium and the dynamics of Arp2/3 complex in that filopodium. Images are taken from timelapse movie frames captured every 10 seconds. Scale bar 5 μm.

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Johnston et al. BMC Cell Biology 2008 9:65   doi:10.1186/1471-2121-9-65