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Pharmacological agents used to uncover ions and molecular mediators involved in carbachol-induced pigment granule dispersion |
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| Drug |
Target/effect |
Concentration |
Reference |
|
|
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| Verapamil |
L-type Ca2+ channel antagonist |
10 μM, 100 μM |
[29] |
| BAPTA-AM |
Intracellular Ca2+ chelator |
1 μM, 30 μM |
[21] |
| Cypermethrin |
PP2B (calcineurin) inhibitor |
100 pM |
[30] |
| Staurosporine |
PKC inhibitor |
100 nM, 0.5 μM, 1 μM |
[25] |
| Bisindolylmaleimide II |
PKC inhibitor |
20 nM, 200 nM, 2 μM |
[31] |
| Phorbol 12-myristate 13-acetate |
PKC activator |
1 μM, 10 μM, 100 μM |
[25] |
|
Drug concentrations used are justified by the articles referenced. All agents were purchased from Sigma-Aldrich (St. Louis, MO). | |||
Johnson and García BMC Cell Biology 2007 8:53 doi:10.1186/1471-2121-8-53 |
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