Table 1

Pharmacological agents used to uncover ions and molecular mediators involved in carbachol-induced pigment granule dispersion

Drug
Target/effect
Concentration
Reference

Verapamil
L-type Ca2+ channel antagonist
10 μM, 100 μM
[29]
BAPTA-AM
Intracellular Ca2+ chelator
1 μM, 30 μM
[21]
Cypermethrin
PP2B (calcineurin) inhibitor
100 pM
[30]
Staurosporine
PKC inhibitor
100 nM, 0.5 μM, 1 μM
[25]
Bisindolylmaleimide II
PKC inhibitor
20 nM, 200 nM, 2 μM
[31]
Phorbol 12-myristate 13-acetate
PKC activator
1 μM, 10 μM, 100 μM
[25]

Drug concentrations used are justified by the articles referenced. All agents were purchased from Sigma-Aldrich (St. Louis, MO).

Johnson and García BMC Cell Biology 2007 8:53   doi:10.1186/1471-2121-8-53