Localization of pSmad1 (A) and pSmad2 (B) in lens epithelial (LE) and fiber cells (LF). There is obvious nuclear localization of pSmad1 and pSmad2 in the fiber cells, where as the nuclear localization is hardly discernible in the epithelial cells. Punctate staining is abundant in the cytoplasm of epithelial and fiber cells. Nuclei are labeled using TOPRO (blue).
Rajagopal et al. BMC Cell Biology 2007 8:25 doi:10.1186/1471-2121-8-25