Table 1

Percentage of CpG methylation in the LEP, PPARG2, FABP4 and LPL promoters in undifferentiated and differentiated ASC clones at passage 4 (P4) and at senescence (Ps)

Percent methylated cytosines in promoter region examined


Gene

LEP

PPARG2

FABP4

LPL


Passage No.

P4

Ps

P4

Ps

P4

Ps

P4

Ps


Undifferentiated

ASC clone

B1

9

17a

10

20c

15

45a

20

8a

B2

7

14a

15

18ns

30

25ns

27

26ns

B3

24

24ns

29

23ns

50

75a

19

19ns


Differentiated

ASC clone

B1

13

13ns

5

33a

12

13ns

17

11ns

B2

4

17a

17

25c

22

25ns

29

24ns

B3

22

38a

17

22ns

50

70b

18

14ns


Chi-square tests: a P < 0.001; b P < 0.005; c P < 0.05; ns non-significant.

Noer et al. BMC Cell Biology 2007 8:18   doi:10.1186/1471-2121-8-18

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