Table 1

Quantitative mutation suppression.

Strain genotype

Plasmid/insert

Mutation frequencya

Standard deviation

Mutagenesis suppression

(% reduction of vector control)


mutM mutY

pTrc99a vector only

9799

± 2848

NAb

mutM mutY

pTrc99a/OXR1 [21]

773

± 324

* 90

mutM mutY

pTrc99a/NCOA7

0.26

± 0.22

* >99.9

mutM mutY

pTrc99a/OXR2 domain of NCOA7 (657–942)

2635

± 725

* 73

Wild type

pTrc99a vector

0.31

± 0.17

* NA


aMutation frequency (Mutants/107 viable cells). Data represent the averages of at least 6 independent measurements.

b Not Applicable.

Durand et al. BMC Cell Biology 2007 8:13   doi:10.1186/1471-2121-8-13

Open Data