Table 1

Alteration of integrin subunits and uPAR in pancreatic cancer cells in response to IL-1α

Antigen

IL-1α

Mean fluorescence intensity


BxPC-3

Capan-2

SW1990


α3integrin

-

310 ± 18

350 ± 12

411 ± 14

+

383 ± 34a

344 ± 18

399 ± 16

α5integrin

-

40 ± 6

72 ± 9

60 ± 8

+

44 ± 4

68 ± 8

61 ± 6

α6integrin

-

520 ± 21

230 ± 11

441 ± 18

+

833 ± 44a

344 ± 27a

612 ± 32a

αv integrin

-

77 ± 8

61 ± 9

51 ± 8

+

71 ± 7

65 ± 9

58 ± 6

β1integrin

-

997 ± 42

814 ± 31

810 ± 33

+

1229 ± 41a

1183 ± 22a

1322 ± 24a

uPA

-

34 ± 3

42 ± 2

51 ± 5

+

143 ± 10a

166 ± 13a

191 ± 9a

uPAR

-

219 ± 17

299 ± 31

291 ± 18

+

423 ± 26a

588 ± 21a

524 ± 19a


IL-1α, interleukin-1α; uPA, urokinase plasminogen activator; uPAR, urokinase plasminogen activator receptor. All data are expressed as mean ± s.d. The p-values indicate statistical significance between data in controls and presence of IL-α. a p < 0.01.

Sawai et al. BMC Cell Biology 2006 7:8   doi:10.1186/1471-2121-7-8

Open Data