Collagen gene expression in primary fibroblasts from female patient without any history of hernia. Type I and III collagen mRNA was quantified in female CFs (fibroblasts derived from patients without incisional hernia) by RT-PCR analysis. A: Type I collagen mRNA expression; B: Type III collagen mRNA expression; white bars: no estrogen, grey bars: 0.025 ng/ml β-estradiol, black bars: 0.25 ng/ml β-estradiol. Data are presented as mean+/- standard deviation;*p < 0.05 vs. white bars (no estrogen).
Jansen et al. BMC Cell Biology 2006 7:36 doi:10.1186/1471-2121-7-36