Table 1

Cx43 expression and invasive capacity of gliomas maintained in nude mice

Controls

CBX



Tumor

Tumor§

Cx43

(S-S0)/S0

Cells/mm perimeter

(S-S0)/S0

Cells/mm perimeter


T1

TG-4-GEN

+++

1.15 ± 0.23

77 ± 9.4

1.05 ± 0.11

68 ± 5.6

T2

TG-1-HAM

+++

0.56 ± 0.05

81 ± 9.4

0.29 ± 0.08 ***

50 ± 7.5 *

T3

TG-7-ROM

+

0a

-

0a

-

T4

TG-14-RAV

+++

1.11 ± 0.08

73 ± 6.7

0.71 ± 0.04 **

54 ± 4.7 *

T6

TG-5-RAI

+/-

0a

-

0a

-

T7

TG-14-CHA

+++

0.45 ± 0.08

48 ± 4.2

0.22 ± 0.01 ***

35 ± 4.4 *

T8

TG-20-THO

+/-

0a

-

0a

-


a, cut off : a tumor which exhibited less than 15 migrating cells distance of migration, if any, less than 50 μm, was considered non invasive.

§ Xenograft tumor nomenclature as originally described by Leuraud et al (2003).

n = 7–10 per group and condition. ***, p < 0.001. **, p < 0.01, *, p < 0.05

Oliveira et al. BMC Cell Biology 2005 6:7   doi:10.1186/1471-2121-6-7

Open Data