Table 1

Cx43 expression and invasive capacity of gliomas maintained in nude mice



Controls
 CBX



Tumor
 Tumor§
 Cx43
 (S-S0)/S0
 Cells/mm perimeter
 (S-S0)/S0
 Cells/mm perimeter
T1
 TG-4-GEN
 +++
 1.15 ± 0.23
 77 ± 9.4
 1.05 ± 0.11
 68 ± 5.6
T2
 TG-1-HAM
 +++
 0.56 ± 0.05
 81 ± 9.4
 0.29 ± 0.08 ***
 50 ± 7.5 *
T3
 TG-7-ROM
 +
 0a
 -
 0a
 -
T4
 TG-14-RAV
 +++
 1.11 ± 0.08
 73 ± 6.7
 0.71 ± 0.04 **
 54 ± 4.7 *
T6
 TG-5-RAI
 +/-
 0a
 -
 0a
 -
T7
 TG-14-CHA
 +++
 0.45 ± 0.08
 48 ± 4.2
 0.22 ± 0.01 ***
 35 ± 4.4 *
T8
 TG-20-THO
 +/-
 0a
 -
 0a
 -

a, cut off : a tumor which exhibited less than 15 migrating cells distance of migration, if any, less than 50 μm, was considered non invasive.

§ Xenograft tumor nomenclature as originally described by Leuraud et al (2003).

n = 7–10 per group and condition. ***, p < 0.001. **, p < 0.01, *, p < 0.05

Oliveira et al. BMC Cell Biology 2005 6:7   doi:10.1186/1471-2121-6-7