Migration assay of glioma cell lines on collagen IV. A, vimentin-immunostained GL15 and 8-MG spheroids, after 4 days of culture on collagen IV without (upper row) and with (lower row) addition of CBX, (x50). B, (S - S0) / S0 ratios (mean values ± SEM) obtained from 10 to 30 spheroids per group and condition. Addition of CBX enhanced spheroid disintegration and centrifugal dispersion of migrating cells. ***, p < 0.001.
Oliveira et al. BMC Cell Biology 2005 6:7 doi:10.1186/1471-2121-6-7