Table 3 |
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Summary of the Sub-cellular Characteristics of Embryos Exposed to Anoxia. |
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Normoxia |
30 Minutes Anoxia (Brief) |
6–12 Hours Anoxia (Intermediate) |
24–72 Hours Anoxia (Long-term) |
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|
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Prophase Blastomeres: |
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Chromosomes Throughout Nucleoplasm |
Chromosomes Aligned Near Nuclear Membrane |
Chromosomes Aligned Near Nuclear Membrane |
Chromosomes Aligned Near Nuclear Membrane |
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Histone H3 Phosphorylation |
Histone H3 Phosphorylation |
Histone H3 Dephosphorylation |
Histone H3 Dephosphorylation |
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Metaphase Blastomeres: |
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Metaphase Plate Normal |
Metaphase Plate Normal |
Metaphase Plate LengthReduced |
Metaphase Plate LengthReduced |
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Histone H3 Phosphorylation |
Histone H3 Phosphorylation |
Histone H3 Phosphorylation |
Histone H3 Dephosphorylation |
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Microtubules Polymerization |
Detectable Microtubule Depolymerization |
Microtubule Spindle Perimeter Reduced |
Microtubule Spindle Perimeter Reduced |
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SAN-1 Localizationat Kinetochore and Nucleoplasm |
SAN-1 Localization at Kinetochore or Lateral Extensions |
SAN-1 Localization at Kinetochore or Lateral Extensions |
SAN-1 Reduced Localization at Kinetochore |
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SAN-1 not essential |
SAN-1 essential |
SAN-1 essential |
SAN-1 essential |
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Interphase Blastomeres: |
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Chromosomes Throughout Nucleoplasm |
Chromosome Condensation |
Chromosome Condensation and Alignment Near Nuclear Membrane |
Chromosome Condensation and Alignment Near Nuclear Membrane |
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|
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Hajeri et al. BMC Cell Biology 2005 6:47 doi:10.1186/1471-2121-6-47 |
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