Table 3

Summary of the Sub-cellular Characteristics of Embryos Exposed to Anoxia.

Normoxia

30 Minutes Anoxia (Brief)

6–12 Hours Anoxia (Intermediate)

24–72 Hours Anoxia (Long-term)


Prophase Blastomeres:

Chromosomes Throughout Nucleoplasm

Chromosomes Aligned Near Nuclear Membrane

Chromosomes Aligned Near Nuclear Membrane

Chromosomes Aligned Near Nuclear Membrane

Histone H3 Phosphorylation

Histone H3 Phosphorylation

Histone H3 Dephosphorylation

Histone H3 Dephosphorylation

Metaphase Blastomeres:

Metaphase Plate Normal

Metaphase Plate Normal

Metaphase Plate LengthReduced

Metaphase Plate LengthReduced

Histone H3 Phosphorylation

Histone H3 Phosphorylation

Histone H3 Phosphorylation

Histone H3 Dephosphorylation

Microtubules Polymerization

Detectable Microtubule Depolymerization

Microtubule Spindle Perimeter Reduced

Microtubule Spindle Perimeter Reduced

SAN-1 Localizationat Kinetochore and Nucleoplasm

SAN-1 Localization at Kinetochore or Lateral Extensions

SAN-1 Localization at Kinetochore or Lateral Extensions

SAN-1 Reduced Localization at Kinetochore

SAN-1 not essential

SAN-1 essential

SAN-1 essential

SAN-1 essential

Interphase Blastomeres:

Chromosomes Throughout Nucleoplasm

Chromosome Condensation

Chromosome Condensation and Alignment Near Nuclear Membrane

Chromosome Condensation and Alignment Near Nuclear Membrane


Hajeri et al. BMC Cell Biology 2005 6:47   doi:10.1186/1471-2121-6-47

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