Regulation of Eps8/Abi1-induced actin remodeling in Xenopus. Distribution of Eps8-myc (A,E,I,M; red in D,H,L,P), actin (B,F,J,N; green in D,H,L,P), CP-GFP (C, blue in D), N-WASP-GFP (G, blue in H), FP4-mito-GFP (K, blue in L), and Xvasp-GFP (O, blue in P). (A-D) CP does not block formation of actin stars. (E-H) N-WASP is recruited to Eps8/Abi1-induced actin stars. Actin star formation is not altered in response to inhibition of Ena/VASP activity (I-L) or increased levels of Xvasp (M-P). Scale bar is equal to 10 μm in A-L and 5 μm in M-P.
Roffers-Agarwal et al. BMC Cell Biology 2005 6:36 doi:10.1186/1471-2121-6-36