Table 1

Cytogenetic data.

Mouse number

Biopsy site

Passage number

Ploidy < 2n

Ploidy = 2n

Ploidy 2n-4n

Ploidy = 4n

Ploidy > 4n

Total number of cells analyzed

Polyploid cells (%)a


Wild-type week 6

30

AM

1

1

29

1

11

10

52

19

31

PF

1

2

46

0

11

0

59

0

31

AM

1

1

26

0

19

4

50

8.0

31

AM

4

0

3

0

3

5

11

45

Wild-type week 12

76

EL

1

2

46

0

4

0

52

0

76

EL

5

0

50

0

17

0

67

0

76

PF

1

0

42

0

7

1

50

2.0

76

AM

1

0

10

0

1

1

12

8.3

77

EL

1

0

60

0

4

0

64

0

77

EL

5

0

22

3

20

5

50

10

77

EL

1

0

46

0

5

1

52

19

77

AM

1

0

85

0

30

2

117

1.7

R6/2 week 6

38

PF

1

0

45

0

5

0

50

0

38

AM

1

0

39

0

12

5

56

8.9

38

AM

4

0

32

0

32

1

65

1.5

38

LC

1

0

24

2

17

7

50

14

39

AM

1

0

33

1

12

4

50

8.0

39

AM

4

0

25

0

30

3

58

5.2

R6/2 week 12

78

EL

1

1

50

0

4

0

55

0

78

EL

5

0

39

1

19

3

62

4.8

78

PF

1

0

53

0

3

0

56

0

78

AM

1

0

30

0

4

1

35

2.9

79

PF

1

0

70

1

7

0

78

0

79

AM

1

0

50

1

7

0

58

0


a Cells with a ploidy level above the tetraploid (4n). AM, abdominal muscle cells; PF, peritoneal fat fibroblasts; EL, ear lobe fibroblasts; LC, liver cells.

Petersén et al. BMC Cell Biology 2005 6:34   doi:10.1186/1471-2121-6-34

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