|
Effect of PE on cell cycle phases. |
||||
| Treatment |
G0/G1 phase |
S phase |
G2/M phase |
% inhibition (S) |
|
|
||||
| vehicle |
9269 ± 0.5 |
319.5 ± 13.5 |
238.5 ± 23.5 |
0 % |
| 2 μM PE |
9770 ± 9.0 |
54.0 ± 2.0 |
125 ± 21.0 |
83% |
| 5 μM PE |
9699 ± 29.0 |
59.0 ± 4.0 |
170 ± 11.0 |
81% |
| 10 μM PE |
9761.5 ± 89.5 |
47.5 ± 13.5 |
110.5 ± 39.5 |
85% |
|
Cells were subjected to flow cytometric DNA analysis as described in Methods. Different concentrations of PE inhibited the re-entry of the cell population into S phase of the cell cycle. Data show the number of cells in each phase of the cell cycle. Values are the mean ± S.E. of three independent experiments performed in duplicate on different batches of cells (Total events per cycle is 10,000 cells). | ||||
Saeed et al. BMC Cell Biology 2004 5:47 doi:10.1186/1471-2121-5-47 |
||||