Table 3

The effect of dephosphorylated IGFBP-1/IGF-1 complex upon the developmental competence of in vivo fertilized mouse zygotes.

Culture medium

Total n

Zygotes arrested in one-cell to

morula stage (%)

Zygotes developed to blastocyst (%)


Blastocyst (%)

Hatched blastocyst (%)


kSOM/AA with

IGFBP-1/IGF-1

93

5(15.4)

88(94.6) **


24(25.5)

64(68.8) *


kSOM/AA without

IGFBP-1/IGF-1

72

13(18.1)

59(81.9) **


22(33.3)

37(48.6) *


The results were pooled from 4 repeats of experiments. * P < 0.05, ** P = 0.050

Lin et al. BMC Cell Biology 2003 4:14   doi:10.1186/1471-2121-4-14

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