Figure 8.

Frequency histogram of the number of fenestrae rows connected to one FFC after 10, 30, 60 and 120 min 100 nM di-h-HALI treatment, extending the static whole-mount TEM images of Figure7. From these histograms it becomes clear that the onset of fenestrae formation starts after 10 min treatment and that the number of fenestrae rows connected to FFCs reaches its maximum at 60 min di-h-HALI treatment. At 120 min of treatment, when the burst of fenestrae formation has subsided (see also, Fig. 7E), a significant shift towards a low number of connected fenestrae rows could be registered.