Figure 1.

A, Positions of the transcription activation (TA), DNA binding (basic) and dimerization (ZIP) domains along the linear sequence of C/EBPα. The numbers below the C/EBPα diagram indicate the amino acid positions at the boundaries of the domains. Also shown are C/EBPα sequences involved in known actions with the indicated cell-cycle proteins: p107 [34], p21 [25], CDK2 [25,36], CDK4 [36] and E2F [33]. B, Schematic of the GFP fusions with full-length and mutant C/EBPα used in the studies reported here.