Additional file 1.
Movie demonstrating mitosis abnormalities in p53-/- Clara cells Clara cells isolated and cultured from gene-targeted mice germline deficient in p53 display cell division abnormalities whereby nuclei fail to segregate mitotically during the final stage of the cell cycle. Spontaneous binucleation and the formation of multiple spindle poles in these cultures highlight functions of wild type p53 in the formation of bipolar spindles. Movie is stored in a Flash (.swf) format, and can be accessed with Flash, QuickTime, Netscape, and Internet Explorer. The additional file can alternatively be accessed via the following website: http:/ / www.ed.ac.uk/ pathology/ Research/ Research_Interests/ Chris_armit/ clara.htm webcite.
Format: SWF Size: 1.7MB Download file
Armit et al. BMC Cell Biology 2002 3:27 doi:10.1186/1471-2121-3-27