Figure 5.

Effect of P-gp blockers. Addition of the P-gp blocker S9788 in the culture medium blocked completely the effect of rrCNTF at 250 ng/ml (-1.5 vs. +75.7 %), rhLIF at 30 ng/ml (-11.5 vs. + 54.3%) and rhCT-1 at 30 ng/ml (-2.5 vs. +26.1%) on P-gp expression in astrocytes.