C-Raf kinase inhibits the VDAC channel function. Single channel recordings of purified rat liver VDAC protein in a DiphPC membrane. VDAC or Bcl-2ΔTm were preincubated with active GST-C-RafDD, inactive GST-C-RafK375W, or GST recombinant proteins before channel conductance measurement (A, B).
Le Mellay et al. BMC Cell Biology 2002 3:14 doi:10.1186/1471-2121-3-14