Immunofluorescence localization of β-dystroglycan and associated components in skeletal muscle fibres from dystrophic animal models. Shown are cryosections labeled with antibodies to laminin (LAM) (a-c), α-dystroglycan (α-DG) (d-f), β-dystroglycan (β-DG) (g-i), the carboxy-terminus of dystrophin (C-DYS) (j-l), utrophin (UTR) (m, o, q), α-sarcoglycan (α-SG) (s-u), and spectrin (SPE) (v-x). Panels (n), (p) and (r) represent labeling of tissue sections with α-bungarotoxin (α-BGT). Skeletal muscle specimens were taken from normal mice (a, d, g, j, m, n, s, v), mdx mice (b, e, h, k, o, p, t, w) and mdx-3cv mice (c, f, i, l, q, r, u, x). Bar = 60 μm.
Culligan et al. BMC Cell Biology 2001 2:2 doi:10.1186/1471-2121-2-2