Table 1

Development of diabetes in ZDF (zucker fatty rat) was monitored by measurement of HbA1c, glucose and body weight
Wk 7 Wk 9 Wk 11 Wk 13 Wk 15 Wk 17
Glucose (mmol/l)
Lean 7.8±0.4 8.9±0.1 8.3±0.2 8.3±0.2 8.5±0.3 8.3±0.2
ZDF 9.2±1.4* 9.9±0.6* 9.2±0.4* 9.6±0.4* 10.6±1.0* 11.0±1.0*
HbA1c (%)
Lean 2.9±0.01 3.4±0.02 3.4±0.05
ZDF 3.3±0.04* 4.8±0.13* 5.0±0.24*
Body weight (g)
Lean 211±5 247±4 280±3 317±5 314±6 365±5
ZDF 252±7* 332±9* 395±7* 449±5* 486±7* 504±9*

Body weight, HbA1c levels, and blood glucose levels are significantly increased in ZDF compared to Lean rats as measured in week 7 to week 17. * < 0.05 = different from controls (Lean) at the same stage.

Talaei et al.

Talaei et al. BMC Cell Biology 2014 15:1   doi:10.1186/1471-2121-15-1

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