Less apoptosis and more survival of CD44+117+CSCs than SKOV-3 cells in 3D culture versus 2D one. A shows the cell apoptotic results detected by Cell Titer-Glo® Luminescent cell viability measurement. B indicates the survival cell numbers in the 3D and 2D culture respectively, from the test by Survival assay. Statistically significant differences are indicated by asterisk (*) for P < 0.05 or (**) for P < 0.03.
Chen et al. BMC Cell Biology 2013 14:7 doi:10.1186/1471-2121-14-7