Localization and translocation dynamics of GxcC ARM coincides with Rap activation. (A) Confocal images of starved cells expressing GFP-RalGDS, GFP-ARM or GFP-GxcC in buffer, 4 sec after cAMP stimulation or in a gradient of cAMP (B) Time-course of RalGDS, GFP-ARM or GFP-FL GxcC translocation from cytoplasm to the membrane upon stimulation with 1μM cAMP. Shown are the mean and SEM of at least 9 cells.
Plak et al. BMC Cell Biology 2013 14:6 doi:10.1186/1471-2121-14-6