Homology models of wildtype Sec61p and Sec61∆L7p in the ER membrane. Side view of homology model of wildtype Sec61p (left) and Sec61∆L7p mutant (right). TM7, TM8 and their connecting loop (Loop 7) are highlighted in green (wildtype) and red (∆L7). Parts of the protein that remain unchanged are shown in shades of yellow. The membrane is indicated in light gray.
Tretter et al. BMC Cell Biology 2013 14:56 doi:10.1186/1471-2121-14-56