TAGLN enhances tumor metastasis by upregulated MMP-2. A: MMP-2 expression in CAF decresed obviously after TAGLN RNAi by ELISA. *, P < 0.05 by one-way analysis of variance (ANOVA). Error bars depict the standard error around the mean. B: knockdown TAGLN impaired the ability of CAF to secret MMP-2 by gelatin zymography.
Yu et al. BMC Cell Biology 2013 14:17 doi:10.1186/1471-2121-14-17