Nimotuzumab inhibits cell invasion. A: Starved cells were allowed to invade the membrane for 72 h in the presence or absence of nimotuzumab followed by the treatment with hEGF. Tca8113 and ACC-M cell invasive ability were markedly inhibited by nimotuzumab. Magnification,×200. B: The quantitative analysis of invaded cells, which were eluted using 10% acetic acid, and the OD value at 570 nm.
Huang et al. BMC Cell Biology 2013 14:13 doi:10.1186/1471-2121-14-13