Nimotuzumab influences the expression of EGFR and its downstream molecules. A, B: Protein level of MMP-9, EGFR, pEGFR, ERK, pERK, Snail, KGF, P-38, and pP38 in control and nimotuzumab- treated group were measured by Western blot. The GAPDH levels were used as the internal controls. C: Densitometric analysis of the expression level of the same proteins relative to GAPDH expression. Error bars indicate mean ± SD; n = 3 experiments; *P < 0.05.
Huang et al. BMC Cell Biology 2013 14:13 doi:10.1186/1471-2121-14-13