Knockdown of ceMTM3 causes loss of muscle fibers in adult C. elegans. Normal N2 and RW1596 worms were cultured on NGM plates containing E. coli cells carrying vector control or ceMTM3 RNAi from the time they were hatched from eggs. A. Alexa Fluor 568- phalloidin staining of muscle fibers in normal N2 worms at indicated ages. B. Images of GFP-positive muscle fibers and quantification of GFP intensity in day 3 and day 5 transgenic RW1596 worms which express a GFP::myosin heavy chain A fusion protein. Data represents mean ± SD (n=50). *** p < 0.001.
Yu et al. BMC Cell Biology 2012 13:28 doi:10.1186/1471-2121-13-28