Altered miRNAs are shared among functionally relevant categories. (a-d) Heatmaps of altered miRNAs grouped into functionally relevant categories: only miRNAs that were altered in the indicated comparisons were included in generating the heatmaps per grouping. Underlined miRNAs were further tested for microarray agreement via q-PCR. (a) Combination of both hyperthermic stress and dystrophy, (b) differential response based on stress in mutants, (c) dependent on the loss of Dg and (d) dependent on the loss of Dys. (e) Stress, dystrophy and Dg/Dys signaling all can cause altered levels of miRNAs that are common among each category showing a functional link in these processes.
Marrone et al. BMC Cell Biology 2012 13:26 doi:10.1186/1471-2121-13-26