Effect of JNK inhibition on human TGF-β1 BAL fluid levels. NB TGF-β1 TG and WT liter-mate control mice on dox or regular water, with or without treatment with JNKi, were sacrificed at PN10, with activation of TGF-β1 at PN7. Bronchoalveolar lavage fluid concentrations of human TGF-β1 were measured. The noted values represent assessments in a minimum of 3 animals in each group. NB: newborn; WT: wild type; TGF-β1: transforming growth factor beta1 transgenic; Reg: regular water; Dox: doxcycline water; JNKi: JNK inhibitor; BAL: bronchoalveolar lavage fluid; h: human. #P ≤ 0.02.
Li et al. BMC Cell Biology 2011 12:54 doi:10.1186/1471-2121-12-54