Effects of polydatin on the expression of sPLA2/cPLA2 mRNA in rat lung. A. Relative expression of sPLA2, quantified by real-time PCR. B. Relative expression of cPLA2, quantified by real-time PCR. I: sham operation group, injected with normal saline; II: endotoxic shock group, injected with LPS (10 mg·kg-1 body weight); III: PD treatment group, injected with LPS (10 mg·kg-1 body weight), then a 0.5% PD solution (0.2 ml·kg-1 body weight) 1 hour later; IV: PD pretreatment group, injected with a 0.5% PD solution (0.2 ml·kg-1 body weight), then LPS (10 mg·kg-1 body weight) 0.5 hours later; V: PD control group. bP < 0.05 and cP < 0.01 vs. group I; fP < 0.01 vs. group II; iP < 0.05 and jP < 0.01 vs. group III.
Shiyu et al. BMC Cell Biology 2011 12:31 doi:10.1186/1471-2121-12-31