Table 2

Mitotic index and occurrence of multipolar mitoses in normal esophageal epithelial cells and esophageal cancer cells.

A

ESCC

BAC

EPC-hTERT

OE21

Kyse-410

OE33

OE19


Experiment

cells

mitoses

%

cells

mitoses

%

cells

mitoses

%

cells

mitoses

%

cells

mitoses

%


1

107

1

0.9

100

6

6.0

113

3

2.6

112

6

5.4

102

1

1.0


2

107

1

0.9

105

4

3.8

101

2

2.0

100

1

1.0

112

5

4.5


3

100

1

1.0

102

4

3.9

109

2

1.8

108

4

3.7

124

5

4.0


mitotic index (Ø)

1.0 ± 0.0%

4.6 ± 1.2%

2.2 ± 0.4%

3.4 ± 2.2%

3.2 ± 1.9%


B

ESCC

BAC

EPC-hTERT

OE21

Kyse-410

OE33

OE19


Experiment

mitoses

multipolar mitoses

%

mitoses

multipolar mitoses

%

mitoses

multipolar mitoses

%

mitoses

multipolar mitoses

%

mitoses

multipolar mitoses

%


1

81

0

0.0

100

13

13.0

101

8

7.9

104

19

18.3

101

2

2.0


2

100

1

1.0

100

7

7.0

100

7

7.0

100

10

10.0

101

1

1.0


3

84

0

0.0

100

3

3.0

100

4

4.0

100

13

13.0

100

0

0.0


multipolar mitoses (Ø)

0.3 ± 0.6%

7.7 ± 5.0%

6.3 ± 2.0%

13.8 ± 4.2%

1.0 ± 1.0%


(A) Summary of the evaluation of the mitotic index. In three independent experiments, about 100 cells were counted and the number of mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of mitoses. (B) Summary of the evaluation of the index of multipolar mitoses. In three independent experiments, about 100 mitoses were counted and the number of multipolar mitoses therein was determined after Aurora-A immunofluorescence staining. The table also provides mean and ± standard deviation of the percentage of multipolar mitoses.

Fichter et al. BMC Cell Biology 2011 12:13   doi:10.1186/1471-2121-12-13

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