Table 1 |
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|
Ten first down and upregulated genes at P0 in hypoxia. |
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|
Gene |
Fold expression H/N |
Genbank Accession |
Putative Function |
|
|
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|
Down Regulated |
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|
RRM2 |
5.94 |
Ribonucleotide Reductase |
|
|
XRCC2 |
5.80 |
X Ray damage DNA Repair |
|
|
KIF24 |
5.16 |
Kinesin: chromatid assembly |
|
|
POLQ |
4.99 |
DNA polymerase theta |
|
|
E2F8 |
4.95 |
Cell cycle progression |
|
|
FANCD2 |
4.93 |
DNA Repair |
|
|
ESCO2 |
4.86 |
Sister chromatid cohesion |
|
|
AURKB |
4.74 |
Chromosome segregation |
|
|
CENPN |
4.48 |
Binding to Centromeres |
|
|
MKI67 |
4.46 |
Cell proliferation |
|
|
Up Regulated |
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|
TCF1 |
6.96 |
Hepatic Transcription Factor |
|
|
LEP |
6.39 |
Metabolism, apoptosis, angiogenesis |
|
|
ANGPT2 |
5.69 |
Antagonise vascular remodelling |
|
|
ZP1 |
5.47 |
Sperm binding to zona pellucida |
|
|
VWF |
5.41 |
Platelet binding to endothelium |
|
|
GIMAP4 |
5.37 |
T-cell development, Tumor suppressor ? |
|
|
CD93 |
4.56 |
Intercellular adhesion, clearance apoptotic cells |
|
|
PLVAP |
4.25 |
Adhesion of Vascular Endothelial cells ? |
|
|
ESAM |
4.24 |
Adhesion of Endothelial cells |
|
|
PCDH17 |
4.14 |
Cell-cell connexions in the brain |
|
|
|
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|
Comparative analysis of transcriptome from MSC at P0 in hypoxia versus normoxia. Mean from 3 distinct samples. |
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|
Basciano et al. BMC Cell Biology 2011 12:12 doi:10.1186/1471-2121-12-12 |
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