Additional file 5.
Figure S4: Classification of differentially expressed genes into pathways. Using the Affymetrix database, the number of genes showing a change in their expression level (indicated on the Y axis of each bar chart) in F111 NA16, colony derived and tumour derived cells was calculated in relative to the F111 A16 cells. The genes were classified into 14 categories as indicated on the X-axis. Panel A represents the total number of genes analysed, with high number of genes which were associated for tumor formation and metastasis, Panel B represents the number of up regulated genes, which were increased in F111 NA16 cells and Panel C represents number of down regulated genes. The encircled gene categories were analysed further by QPCR and immunofluorescence validation.
Format: TIFF Size: 3.3MB Download file
Jinka et al. BMC Cell Biology 2010 11:93 doi:10.1186/1471-2121-11-93