Adenoviral mediated overexpression of HIF-1alpha and HIF-1alphaDELTAODD can up-regulate the transcription of MICA on HK-2 cells in normoxia. The relative mRNA levels were determined by real-time PCR and normalized to the housekeeping gene β-actin. Values are shown as means ± SD from three independent experiments. *indicates significant difference compared with the control group (p < 0.05).
Luo et al. BMC Cell Biology 2010 11:91 doi:10.1186/1471-2121-11-91