Table 2

Phospholipid profile of transfected MLE-12 cells stably expressing mutant SP-CI73T.

WT

I73T

P (Anova)


Total phospholipids (nmol/mg protein)

152.80 ± 9.6

153.10 ± 10.0

ns

Phospholipid classes (% of total PL)

Phosphatidylcholine

57.80 ± 1.0

53.70 ± 0.8

< 0.001

Lyso-Phosphatidylcholine

0.60 ± 0.1

1.00 ± 0.8

< 0.001

Phosphatidylglycerol

0.30 ± 0.0

0.20 ± 0.1

ns

Sphingomyelin

6.20 ± 0.3

5.50 ± 0.2

< 0.05

Ceramide

1.80 ± 0.1

1.80 ± 0.1

ns

Glucosyl-Ceramide

0.10 ± 0.0

0.10 ± 0.0

ns

Phosphatidylethanolamine

11.20 ± 0.5

14.70 ± 0.8

< 0.001

Phosphatidylserine

6.50 ± 0.1

6.60 ± 0.3

ns


Data are means of three independent experiments each performed in duplicate. P-values are given.

Woischnik et al. BMC Cell Biology 2010 11:88   doi:10.1186/1471-2121-11-88

Open Data