Table 1 |
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|
Chaperone level in MLE-12 cells expressing mutant SP-CI73T in response to drugs used in ILD therapy. |
||||
|
HSP 90 |
Calreticulin |
HSP 70 |
Calnexin |
|
|
|
||||
|
Cyclophosphamide |
+ 30% * |
+ 13% * |
+ 41% * |
+ 16% |
|
Azathioprine |
+36% * |
+ 8% |
+ 7% |
- 13% |
|
Hydroxychloroquine |
+ 81% * |
+ 75% * |
+ 18% |
+ 6% |
|
Methylprednisolone |
+ 55% * |
+ 26% * |
+ 8% |
- 9% |
|
|
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|
Presented are the results of three independent experiments and expressed as % changes of the protein amounts in SP-CI73T cells compared to SP-CWT expressing cells; * denotes p-values < 0.05 |
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|
Woischnik et al. BMC Cell Biology 2010 11:88 doi:10.1186/1471-2121-11-88 |
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