Motif 1 is a mediator of nutrition-dependent transcription. A. Heat-maps showing expression profiles of Cluster A and Cluster B genes. Columns indicate expression changes at different AA starvation/re-feeding time-points B. Weblogos of two motifs enriched in the promoters of AA starvation-regulated genes. C, D. Real-time qPCR data from transgenic larvae carrying promoter-GFP reporters for two different starvation-regulated genes. Black bars, wild-type promoter, Grey bars, motif1-mutated promoters. E. Real-time qPCR data from transgenic larvae carrying 5× motif1-GFP reporter.
Li et al. BMC Cell Biology 2010 11:7 doi:10.1186/1471-2121-11-7