Protein starvation regulates gene expression in Drosophila larvae. A. Heat map depicting temporal patterns of changing gene expression following starvation and subsequent re-feeding. Left panel, transcripts induced by starvation and reversed by re-feeding. Right panel, transcripts suppressed by starvation and reversed by re-feeding. Columns indicate expression changes at different AA starvation/re-feeding time-points B. Gene classes whose expression was down-regulated at 24 h following protein starvation. Blue shading indicates metabolic genes, red shading indicates ribosome and/or protein synthesis genes. C, Gene classes whose expression was up-regulated at 24 h following protein starvation. Blue shading indicates metabolic genes.
Li et al. BMC Cell Biology 2010 11:7 doi:10.1186/1471-2121-11-7