Mouse EPCs do not display evidence of transformation. The evaluation of anchorage-independent growth was examined in mouse EPCs and cells derived from a beta cell tumour seeded onto a soft agar matrix. Whereas EPCs did not grow on soft agar, beta tumour cells (used as control) formed frequent colonies during the 8 days of cultivation. 50-fold.
Schniedermann et al. BMC Cell Biology 2010 11:50 doi:10.1186/1471-2121-11-50