Mouse lung EPCs retain a microvascular endothelial phenotype. Immunophenotyping of cells was performed with flow cytometric analyses. Mouse lung EPCs express the pan-endothelial markers CD31, CD102 and CD105. They also express circulating EPC markers CD34, CD133, vascular endothelial growth factor receptors 2 and 3 (VEGFR-2 + VEGFR-3). The new marker LA5 and MECA32/PV1 for blood endothelial cells (BEC) is also expressed as well as the lymphatic markers Lyve1 and podoplanin. The pan-lymphocyte marker CD45 was not detectable.
Schniedermann et al. BMC Cell Biology 2010 11:50 doi:10.1186/1471-2121-11-50